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Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. EHP is published by the National Institute of Environmental Health Sciences and its content is free online. Print issues are available by paid subscription.DISCLAIMER
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Environmental Health Perspectives Supplements Volume 101, Number S4, 1993 Open Access
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Basic Problems in Interaction Assessment

Sander Greenland

Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA 90024-1772

Abstract

This paper reviews problems with the definition and estimation of interactions in epidemiologic studies. Methods for modeling interactions and dose-response also are reviewed, and references to more detailed literature are provided. Concepts are illustrated in the context of evaluating the joint effects of household radon exposure and environmental tobacco smoke. -- Environ Health Perspect 101(Suppl 4) :59-66 (1993) .

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