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Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. EHP is published by the National Institute of Environmental Health Sciences and its content is free online. Print issues are available by paid subscription.DISCLAIMER
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Environmental Health Perspectives Supplements Volume 101, Number S4, 1993 Open Access
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Examining Acute Health Outcomes Due to Ozone Exposure and Their Subsequent Relationship to Chronic Disease Outcomes

Bart D. Ostro

Air Pollution Epidemiology Unit, California Office of Environmental Health Hazard Assessment, Berkeley Way, Annex 11, Berkeley, CA 94704

Abstract

Current evidence indicates that individuals exposed to short term elevations in ambient ozone may experience both upper and lower respiratory effects. Some respiratory symptoms and spirometric changes are mild and reversible in nature, while others involve more severe outcomes, including hospital admissions and emergency room visits. However, many questions remain about the effects of acute ozone exposure and the implications of this exposure for chronic disease outcomes. For example, the identification of sensitive subgroups, the delineation of the entire spectrum of health effects due to exposure to ozone, the potential synergy between viral infections and ozone exposure, and the nature of adaptation to ozone are not well characterized. In addition, studies that examine the association between acute responses to ozone and potential biological indicators of a chronic disease process would be desirable. This paper serves to provide an overview of the types of epidemiologic studies that may be appropriate and factors to consider in addressing these questions. -- Environ Health Perspect 101(Suppl 4) :213-216 (1993) .

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