| Environmental Health Issues Leslie L. Robison,1 Jonathan D. Buckley,2 and
Greta Bunin3
For the Childrens Cancer Group Epidemiology Committee 1Division of Pediatric Epidemiology/Clinical Research, University
of Minnesota, Minneapolis, Minnesota; 2Department of Preventive
Medicine, University of Southern California School of Medicine, Los Angeles,
California; 3Division of Oncology, Children's Hospital of Philadelphia,
Philadelphia, Pennsylvania Abstract
The occurrence of cancer during childhood represents one of the leading causes of death within the pediatric and adolescent age group. It is estimated that approximately 8000 children will be diagnosed annually with cancer in the United States. Epidemiologic research addressing the etiology of childhood cancer has been limited because of the difficulties in identifying a sufficiently large study population. Moreover, the use of retrospectively ascertained childhood cancer cases in epidemiologic investigations has restricted the incorporation of biological and clinical parameters. The Childrens Cancer Group has developed an active program in epidemiologic research, with over a decade of experience demonstrating the feasibility and strengths of conducting analytic epidemiologic studies within a cooperative clinical trials network. The availability of detailed clinical and biologic data on cases diagnosed within the cooperative group facilitates the transfer of state-of-the-art technology to epidemiologic research. -- Environ Health Perspect 103(Suppl 6) :111-116 (1995) Key words: pediatric cancers, etiology, biological markers, clinical/pathologic features
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