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Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. EHP is published by the National Institute of Environmental Health Sciences and its content is free online. Print issues are available by paid subscription.DISCLAIMER
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Environmental Health Perspectives Supplements Volume 107, Number S4, August 1999
Environmental Health Perspectives Supplements August 1999 Supplement to the Carcinogenic Potency Database

Effects of Endocrine Disruptors at Environmental Exposure Levels

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Identifying chemicals that have the potential to cause cancer or disrupt the endocrine systems is the theme of the current Issue. Included are a supplement to a widely used cancer database and an evaluation of low dose effects of endocrine disruptors.

Supplement to the Carcinogenic Potency Database

Supplement to the Carcinogenic Potency Database (CPDB): Results of Animal Bioassays Published in the General Literature in 1993 to 1994 and by the National Toxicology Program in 1995 to 1996
Lois Swirsky Gold, Neela B. Manley, Thomas H. Slone, and Lars Rohrbach
p. 527

Supplemental Plot of the Carcinogenic Potency Database
p. 535

Appendices

Appendix 1. Species
p. 590

Appendix 2. Strain Codes and Definitions
p. 590

Appendix 3. Routes of Administration
p. 591

Appendix 4. Site Codes
p. 591

Appendix 5. Histopathology
p. 591

Appendix 6. Notecodes and Definitions
p. 593

Appendix 7. Dose-Response Curve and Plot Symbols
p. 593

Appendix 8. Author's Opinion
p. 593

Appendix 9. Berkeley Codes
p. 593

Appendix 10. Journals
p. 594

Appendix 11. Chemical Names and Synonyms in this Plot
p. 594

Appendix 12. Chemical Names in this Plot Listed by CAS Number
p. 596

Appendix 13. Bibliography: National Toxicology Program Technical Reports
p. 598

Appendix 14. Bibliography: General Literature
p. 598

Effects of Endocrine Disruptors at Environmental Exposure Levels

Introduction--Workshop on Characterizing the Effects of Endocrine Disruptors on Human Health at Environmental Exposure Levels
Ronald L. Melnick
p. 603

An Approach to the Development of Quantitative Models to Assess the Effects of Exposure to Environmentally Relevant Levels of Endocrine Disruptors on Homeostasis in Adults
Nira Ben-Jonathan, Ralph L. Cooper, Paul Foster, Claude L. Hughes, Patricia B. Hoyer, Diane Klotz, Michael Kohn, Dolores J. Lamb, and George M. Stancel
p. 605

Evaluating the Effects of Endocrine Disruptors on Endocrine Function during Development
Robert Bigsby, Robert E. Chapin, George P. Daston, Barbara J. Davis, Jack Gorski, L. Earl Gray, Kembra L. Howdeshell, R. Thomas Zoeller, and Frederick S. vom Saal
p. 613

Species, Interindividual, and Tissue Specificity in Endocrine Signaling
Cheryl Walker, S. Ansar Ahmed, Terry Brown, Shuk-Mei Ho, Leslie Hodges, George Lucier, Jose Russo, Nancy Weigel, Tom Weise, and John Vandenbergh
p. 619

New Approaches for Estimating Risk from Exposure to Diethylstilbestrol
Gerald R. Cunha, John-Gunnar Forsberg, Robert Golden, Arthur Haney, Taisen Iguchi, Retha Newbold, Shanna Swan, and Wade Welshons
p. 625

Quantitative Mechanistically Based Dose-Response Modeling with Endocrine-Active Compounds
Melvin E. Andersen, Rory B. Conolly, Elaine M. Faustman, Robert J. Kavlock, Christopher J. Portier, Daniel M. Sheehan, Patrick J. Wier, and Lauren Ziese
p. 631

Characterization of Potential Endocrine-Related Health Effects at Low-Dose Levels of Exposure to PCBs
Abraham Brouwer, Matthew P. Longnecker, Linda S. Birnbaum, Jim Cogliano, Paul Kostyniak, Jack Moore, Suzan Schantz, and Gerhard Winneke
p. 639

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