| Air Pollution and Daily Mortality in Three U.S. Counties Suresh H. Moolgavkar Fred Hutchinson Cancer Research Center and Sciences International, Inc, Seattle, Washington, USA Abstract
I used generalized additive models to analyze the time-series of daily total nonaccidental and cause-specific (cardiovascular, cerebrovascular, and chronic obstructive pulmonary disease) deaths over the period 1987-1995 in three major U.S. metropolitan areas: Cook County, Los Angeles County, and Maricopa County. In all three counties I had monitoring information on particulate matter  10 µm (PM10) , carbon monoxide, sulfur dioxide, nitrogen dioxide, and ozone. In Los Angeles, monitoring information on particulate matter 2.5 µm (PM2.5) was available as well. I present the results of both single and multi-pollutant analyses. Air pollution was associated with each of the mortality end points. With respect to the individual components of the pollution mix, the results indicate considerable heterogeneity of air pollution effects in the different geographic locations. In general, the gases, particularly CO, but not ozone, were much more strongly associated with mortality than was particulate matter. This association was particularly striking in Los Angeles County. Key words: carbon monoxide, cardiovascular disease, cerebrovascular disease, chronic obstructive pulmonary disease, nitrogen dioxide, ozone, particulate matter, sulfur dioxide. Environ Health Perspect 108:777-784 (2000) . [Online 12 July 2000] http://ehpnet1.niehs.nih.gov/docs/2000/108p777-784moolgavkar/ abstract.html Address correspondence to S.H. Moolgavkar, Fred Hutchinson Cancer Research Center, Division of Public Health Sciences - MP 665, 1100 Fairview Avenue N., Seattle, WA 98109 USA. Telephone: (206) 667-4273 ; Fax: (206) 667-7004. E-mail: smoolgav@fhcrc.org I thank E.G. Luebeck for computational support. This work was supported by the American Iron and Steel Institute. Received 29 February 2000 ; accepted 11 April 2000.
The full version of this article is available for free in HTML or PDF formats. |
