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| Epidemiologic Evidence of Cardiovascular Effects of Particulate Air Pollution Douglas W. Dockery Abstract In the past decade researchers have developed a body of epidemiologic evidence showing increased daily cardiovascular mortality and morbidity associated with acute exposures to particulate air pollution. Associations have been found not only with cardiovascular deaths reported on death certificates but also with myocardial infarctions and ventricular fibrillation. Particulate air pollution exposure has been associated with indicators of autonomic function of the heart including increased heart rate, decreased heart rate variability, and increased cardiac arrhythmias. Several markers of increased risk for sudden cardiac death have also been associated with such exposures. These epidemiologic studies provide early guidance to possible pathways of particulate air pollution health effects, which can only be addressed fully in toxicologic and physiologic studies. Key words: air pollution, cardiovascular disease, epidemiology, particles. -- Environ Health Perspect 109(suppl 4) :483-486 (2001) . http://ehpnet1.niehs.nih.gov/docs/2001/suppl-4/483-486dockery/abstract.html The full version of this article is available for free in HTML or PDF formats. |
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