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Environmental Health Perspectives Supplements Volume 110, Number S3, June 2002
Environmental Health Perspectives Supplements June 2002 Impact of Endocrine Disruptors on Brain Development and Behavior

Special Report: Cancer Risk Assessment for Polycyclic Aromatic Hydrocarbons

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“… it is imperative that we assure that all children are born with the ability to love, socially integrate, and reach their fullest intellectual potential….” – Theo Colborn

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Impact of Endocrine Disruptors on Brain Development and Behavior

Preface


Theo Colborn
p. 335

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Disruption of the Thyroid System

A Model of the Development of the Brain as a Construct of the Thyroid System


Kembra L. Howdeshell
p. 337

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Goitrogenic and Estrogenic Activity of Soy Isoflavones


Daniel R. Doerge and Daniel M. Sheehan
p. 349

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Thyroid Hormone, Brain Development, and the Environment


R. Thomas Zoeller, Amy L.S. Dowling, Carolyn T.A. Herzig, Eric A. Iannacone, Kelly J. Gauger, and Ruby Bansal Rachel Morello-Frosch, Manuel Pastor Jr., Carlos Porras, and James Sadd
p. 355

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Clues from Wildlife to Create an Assay for Thyroid System Disruption


Theo Colborn
p. 363

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Endocrine Disruption by Polychlorinated Biphenyls and Dioxins

Evidence that GABAergic Neurons in the Preoptic Area of the Rat Brain Are Targets of 2,3,7,8-Tetrachlorodibenzo-p-dioxin during Development


Linda E. Hays, Clifford D. Carpenter, and Sandra L. Petersen
p. 369

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Electrophysiologic and Behavioral Effects of Perinatal and Acute Exposure of Rats to Lead and Polychlorinated Biphenyls


David O. Carpenter, Rifat J. Hussain, David F. Berger, John P. Lombardo, and Hye-Youn Park
p. 377

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Sexually Dimorphic Nonreproductive Behaviors as Indicators of Endocrine Disruption


Bernard Weiss
p. 387

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Disruption of Estrogen and Androgen Responses


Effects of Incubation Temperature and Estrogen Exposure on Aromatase Activity in the Brain and Gonads of Embryonic Alligators


Matthew R. Milnes, Robert N. Roberts, and Louis J. Guillette Jr.
p. 393

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Early Cerebral Activities of the Environmental Estrogen Bisphenol A Appear to Act via the Somatostatin Receptor Subtype sst2


Rosa Maria Facciolo, Raffaella Alò, Maria Madeo, Marcello Canonaco, and Francesco Dessì-Fulgheri
p. 397

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Effects of Perinatal Exposure to Bisphenol A on Play Behavior of Female and Male Juvenile Rats


Francesco Dessì-Fulgheri, Stefania Porrini, and Francesca Farabollini
p. 403

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Effects of Perinatal Exposure to Bisphenol A on Sociosexual Behavior of Female and Male Rats


Francesca Farabollini, Stefania Porrini, Daniele Della Seta, Fiorella Bianchi, and Francesco Dessì-Fulgheri
p. 409

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Exposure to a Low Dose of Bisphenol A during Fetal Life or in Adulthood Alters Maternal Behavior in Mice


Paola Palanza, Kembra L. Howdeshell, Stefano Parmigiani, and Frederick S. vom Saal
p. 415

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The Parvocellular Vasotocin System of Japanese Quail: A Developmental and Adult Model for the Study of Influences of Gonadal Hormones on Sexually Differentiated and Behaviorally Relevant Neural Circuits


Gian Carlo Panzica, Jacques Balthazart, Marzia Pessatti, and Carla Viglietti-Panzica
p. 423

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Aromatase Activity in the Ovary and Brain of the Eastern Mosquitofish (Gambusia holbrooki) Exposed to Paper Mill Effluent


Edward F. Orlando, William P. Davis, and Louis J. Guillette Jr.
p. 429

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Androgens and Environmental Antiandrogens Affect Reproductive Development and Play Behavior in the Sprague-Dawley Rat


A.K. Hotchkiss, J.S. Ostby, J.G. Vandenbergh, and L.E. Gray Jr.
p. 435

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Birth Defects, Season of Conception, and Sex of Children Born to Pesticide Applicators Living in the Red River Valley of Minnesota, USA


Vincent F. Garry, Mary E. Harkins, Leanna L. Erickson, Leslie K. Long-Simpson, Seth E. Holland, and Barbara L. Burroughs
p. 441

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Special Report: Cancer Risk Assessment for Polycyclic Aromatic Hydrocarbons

Cancer Risk Assessment, Indicators, and Guidelines for Polycyclic Aromatic Hydrocarbons in the Ambient Air


Carl-Elis Boström, Per Gerde, Annika Hanberg, Bengt Jernström, Christer Johansson, Titus Kyrklund, Agneta Rannug, Margareta Törnqvist, Katarina Victorin, and Roger Westerholm
p. 451

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