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Joanna S. Jaworska,¹ M. Comber,² C. Auer,³ and C.J. Van Leeuwen⁴

¹Procter & Gamble Eurocor, Strombeek-Bever, Belgium; ²ExxonMobil Biomedical Sciences Inc., Annandale, New Jersey, USA; ³U.S. Environmental Protection Agency, Washington, DC, USA; ⁴European Commission, Joint Research Centre, Institute for Health and Consumer Protection, Ispra, Italy

Abstract
The "Workshop on Regulatory Use of (Q) SARs for Human Health and Environmental Endpoints," organized by the European Chemical Industry Council and the International Council of Chemical Associations, gathered more than 60 human health and environmental experts from industry, academia, and regulatory agencies from around the world. They agreed, especially industry and regulatory authorities, that the workshop initiated great potential for the further development and use of predictive models, that is, quantitative structure-activity relationships [(Q) SARs], for chemicals management in a much broader scope than is currently the case. To increase confidence in (Q) SAR predictions and minimization of their misuse, the workshop aimed to develop proposals for guidance and acceptability criteria. The workshop also described the broad outline of a system that would apply that guidance and acceptability criteria to a (Q) SAR when used for chemical management purposes, including priority setting, risk assessment, and classification and labeling. Key words: quantitative structure-activity relationships, regulatory acceptance. Environ Health Perspect 111:1358-1360 (2003) . doi:10.1289/ehp.5757 available via http://dx.doi.org/ [Online 5 February 2003]