| Key Issues for the Assessment of the Allergenic Potential of Genetically Modified Foods: Breakout Group Reports Dori R. Germolec,1 Ian Kimber,2 Lynn Goldman,3
and MaryJane Selgrade4 1Laboratory of Molecular Toxicology, National Institute
of Environmental Health Sciences, Research Triangle Park, North Carolina,
USA; 2Syngenta Central Toxicology Laboratory, Alderley Park,
Macclesfield, Cheshire, United Kingdom; 3Johns Hopkins University
Bloomberg School of Public Health, Baltimore, Maryland, USA; 4National
Health and Environmental Effects Research Laboratory, Office of Research
and Development, U.S. Environmental Protection Agency, Research Triangle
Park, North Carolina, USA Abstract
On the final afternoon of the workshop "Assessment of the Allergenic Potential of Genetically Modified Foods," held 10-12 December 2001 in Chapel Hill, North Carolina, USA, speakers and participants met in breakout groups to discuss specific questions in the areas of use of human clinical data, animal models to assess food allergy, biomarkers of exposure and effect, sensitive populations, dose-response assessment, and postmarket surveillance. Each group addressed general questions regarding allergenicity of genetically modified foods and specific questions for each subject area. This article is a brief summary of the discussions of each of the six breakout groups regarding our current state of knowledge and what information is needed to advance the field. Key words: animal models, food allergy, hazard identification, IgE, immunoassay, postmarket surveillance, safety assessment, sensitization, skin prick test, threshold. Environ Health Perspect 111:1131-1139 (2003) .
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