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Research Article
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| Biologically Plausible Particulate Air Pollution Mortality Concentration-Response Functions Steven Roberts School of Finance and Applied Statistics, Australian National University, Canberra, Australia Abstract
In this article I introduce an alternative method for estimating particulate air pollution mortality concentration-response functions. This method constrains the particulate air pollution mortality concentration-response function to be biologically plausible--that is, a nondecreasing function of the particulate air pollution concentration. Using time-series data from Cook County, Illinois, the proposed method yields more meaningful particulate air pollution mortality concentration-response function estimates with an increase in statistical accuracy. Key words: air pollution, daily mortality, dose-response relationship, models, particulate matter. Environ Health Perspect 112:309-313 (2004) . doi:10.1289/ehp.6428 available via http://dx.doi.org/ [Online 24 November 2003]
Address correspondence to S. Roberts, School of Finance and Applied Statistics, Australian National University, Crisp Building 026, Canberra ACT 0200, Australia. Telephone: 61 2 612 54508. Fax: 61 2 612 50087. E-mail: spr@stanfordalumni.org I thank P. Switzer for his comments and S. Zeger for the combined Cook County mortality and meteorological data used in this paper. The author was partially supported by a Stanford Graduate Fellowship. The author declares he has no competing financial interests. Received 30 April 2003 ; accepted 24 November 2003.
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