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Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. EHP is published by the National Institute of Environmental Health Sciences and its content is free online. Print issues are available by paid subscription.DISCLAIMER
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Environmental Health Perspectives Volume 115, Number 12, December 2007
Nutrigenomics: The Genome–Food Interface Nutrigenomics: The Genome–Food Interface

M. Nathaniel Mead

Abstract

Nutrigenomics is the study of how nutrients affect the expression of an individual's genetic makeup-the impact of dietary components on the genome, the proteome (the sum total of all proteins) , and the metabolome (the sum of all metabolites) in humans. Researchers recognize that only a proportion of the population will respond positively to specific nutritional interventions, while a number of people will be unresponsive, and some individuals could even be adversely affected. Nutrigenomicists are therefore looking at how the interface of genes and diet may influence the rising rates of health problems such as cardiovascular disease, diabetes, and obesity in countries around the world.


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