HEALTH POLICY | U.S. Funding Is Insufficient to Address the Human Health Impacts of and Public Health Responses to Climate Variability and Change
Kristie L. Ebi, John Balbus, Patrick L. Kinney, Erin Lipp, David Mills, Marie S. O'Neill, and Mark L. Wilson
857 [ Abstract ] [ Full ] [ PDF ]

POPULATION HEALTH | Modern Environmental Health Hazards: A Public Health Issue of Increasing Significance in Africa
Onyemaechi C. Nweke and William H. Sanders III
Also see Science Selections, p. A257
863 [ Abstract ] [ Full ] [ PDF ]

EXPOSURE SCIENCE | A Review of Events That Expose Children to Elemental Mercury in the United States
Robin Lee, Dan Middleton, Kathleen Caldwell, Steve Dearwent, Steven Jones, Brian Lewis, Carolyn Monteilh, Mary Ellen Mortensen, Richard Nickle, Kenneth Orloff, Meghan Reger, John Risher, Helen Schurz Rogers, and Michelle Watters
871 [ Abstract ] [ Full ] [ PDF ]

TOXICOLOGY | Prenatal Exposure to Bisphenol A at Environmentally Relevant Doses Adversely Affects the Murine Female Reproductive Tract Later in Life
Retha R. Newbold, Wendy N. Jefferson, and Elizabeth Padilla-Banks
Also see Science Selections, p. A256
879 [ Abstract ] [ Full ] [ PDF ]

EXPOSURE SCIENCE | Estimating Regional Spatial and Temporal Variability of PM2.5 Concentrations Using Satellite Data, Meteorology, and Land Use Information
Yang Liu, Christopher J. Paciorek, and Petros Koutrakis
886 [ Abstract ] [ Full ] [ PDF ]

TOXICOLOGY | California Wildfires of 2009: Coarse and Fine Particulate Matter Toxicity
Teresa C. Wegesser, Kent E. Pinkerton, and Jerold A. Last
893 [ Abstract ] [ Full ] [ PDF ]

EPIDEMIOLOGY | The Effect of Fine and Coarse Particulate Air Pollution on Mortality: A National Analysis
Antonella Zanobetti and Joel Schwartz
898 [ Abstract ] [ Full ] [ PDF ]

EXPOSURE SCIENCE | Estimating Regional Spatial and Temporal Variability of PM2.5 Concentrations Using Satellite Data, Meteorology, and Land Use Information
Christopher J. Paciorek, and Petros Koutrakis
904 [ Abstract ] [ Full ] [ PDF ]

TOXICOLOGY | Oral Exposure to Bisphenol A Increases Dimethylbenzanthracene-Induced Mammary Cancer in Rats
Sarah Jenkins, Nandini Raghuraman, Isam Eltoum, Mark Carpenter, Jose Russo, and Coral A. Lamartiniere
910 [ Abstract ] [ Full ] [ PDF ]

NEUROTOXICOLOGY | Consumption of a High-Fat Diet in Adulthood Ameliorates the Effects of Neonatal Parathion Exposure on Acetylcholine Systems in Rat Brain Regions
Theodore A. Slotkin, T. Leon Lassiter, Ian T. Ryde, Nicola Wrench, Edward D. Levin, and Frederic J. Seidler
Also see Science Selections, p. A257
916 [ Abstract ] [ Full ] [ PDF ]

REPRODUCTIVE HEALTH | Do Perfluoroalkyl Compounds Impair Human Semen Quality?
Ulla Nordström Joensen, Rossana Bossi, Henrik Leffers, Allan Astrup Jensen, Niels E. Skakkebæk, and Niels Jørgensen
Also see Science Selections, p. A256
923 [ Abstract ] [ Full ] [ PDF ]

PROTEOMICS | Increased Expression of Histone Proteins during Estrogen-Mediated Cell Proliferation
Zheying Zhu, Robert J. Edwards, and Alan R. Boobis
928 [ Abstract ] [ Full ] [ PDF ]

GENE POLYMORPHISM | Postural Changes in Blood Pressure Associated with Interactions between Candidate Genes for Chronic Respiratory Diseases and Exposure to Particulate Matter
Elissa Wilker, Murray A. Mittleman, Augusto A. Litonjua, Audrey Poon, Andrea Baccarelli, Helen Suh, Robert O. Wright, David Sparrow, Pantel Vokonas, and Joel Schwartz
935 [ Abstract ] [ Full ] [ PDF ]

NEUROTOXICOLOGY | A Proton Magnetic Resonance Spectroscopy Study of the Chronic Lead Effect on the Basal Ganglion and Frontal and Occipital Lobes in Middle-Age Adults
Tsyh-Jyi Hsieh, Yi-Chun Chen, Chun-Wei Li, Gin-Chang Liu, Yu-Wen Chiu, and Hung-Yi Chuang
941 [ Abstract ] [ Full ] [ PDF ]

METABOLISM | Evidence That Humans Metabolize Benzene via Two Pathways
Stephen M. Rappaport, Sungkyoon Kim, Qing Lan, Roel Vermeulen, Suramya Waidyanatha, Luoping Zhang, Guilan Li, Songnian Yin, Richard B. Hayes, Nathaniel Rothman, and Martyn T. Smith
946 [ Abstract ] [ Full ] [ PDF ]

EXPOSURE SCIENCE | Biological Monitoring for Depleted Uranium Exposure in U.S. Veterans
Carrie D. Dorsey, Susan M. Engelhardt, Katherine S. Squibb, and Melissa A. McDiarmid
953 [ Abstract ] [ Full ] [ PDF ]

EPIDEMIOLOGY | Emergency Admissions for Cardiovascular and Respiratory Diseases and the Chemical Composition of Fine Particle Air Pollution
Roger D. Peng, Michelle L. Bell, Alison S. Geyh, Aidan McDermott, Scott L. Zeger, Jonathan M. Samet, and Francesca Dominici
957 [ Abstract ] [ Full ] [ PDF ]

GENE POLYMORPHISM | Dopamine Transporter Genetic Variants and Pesticides in Parkinson's Disease
Beate R. Ritz, Angelika D. Manthripragada, Sadie Costello, Sarah J. Lincoln, Matthew J. Farrer, Myles Cockburn, and Jeff Bronstein
964 [ Abstract ] [ Full ] [ PDF ]

POPULATION HEALTH | Progression from Beryllium Exposure to Chronic Beryllium Disease: An Analytic Model
Philip Harber, Siddharth Bansal, and John Balmes
970 [ Abstract ] [ Full ] [ PDF ]

RESPIRATORY DISEASE | Trends in Respiratory Symptoms of Firefighters Exposed to the World Trade Center Disaster: 2001–2005
Mayris P. Webber, Jackson Gustave, Roy Lee, Justin K. Niles, Kerry Kelly, Hillel W. Cohen, and David J. Prezant
975 [ Abstract ] [ Full ] [ PDF ]

GENE EXPRESSION/GENE REGULATION | Perturbation of Defense Pathways by Low-Dose Arsenic Exposure in Zebrafish Embryos
Carolyn J. Mattingly, Thomas H. Hampton, Kimberly M. Brothers, Nina E. Griffin, and Antonio Planchart
981 [ Abstract ] [ Full ] [ PDF ]

RESPIRATORY DISEASE | Pneumoconiosis from Agricultural Dust Exposure among Young California Farmworkers
Marc B. Schenker, Kent E. Pinkerton, Diane Mitchell, Val Vallyathan, Brenda Elvine-Kreis, and Francis H.Y. Green
988 [ Abstract ] [ Full ] [ PDF ]

HUMAN TOXICOLOGY | Effects of Ambient Air Pollution on Hemostasis and Inflammation
Goran Rudež, Nicole A.H. Janssen, Evren Kilinc, Frank W.G. Leebeek, Miriam E. Gerlofs-Nijland, Henri M.H. Spronk, Hugo ten Cate, Flemming R. Cassee, and Moniek P.M. de Maat
995 [ Abstract ] [ Full ] [ PDF ]

EPIDEMIOLOGY | Parental Exposure to Pesticides and Childhood Brain Cancer: U.S. Atlantic Coast Childhood Brain Cancer Study
Youn K. Shim, Steven P. Mlynarek, and Edwin van Wijngaarden
1002 [ Abstract ] [ Full ] [ PDF ]

EPIDEMIOLOGY | Residential Exposure to Polychlorinated Biphenyls and Organochlorine Pesticides and Risk of Childhood Leukemia
Mary H. Ward, Joanne S. Colt, Catherine Metayer, Robert B. Gunier, Jay Lubin, Vonda Crouse, Marcia G. Nishioka, Peggy Reynolds, and Patricia A. Buffler
1007 [ Abstract ] [ Full ] [ PDF ]

ENDOCRINE SYSTEM | Thyroid Hormone Levels of Pregnant Inuit Women and Their Infants Exposed to Environmental Contaminants
Renée Dallaire, Gina Muckle, Éric Dewailly, Sandra W. Jacobson, Joseph L. Jacobson, Torkjel M. Sandanger, Courtney D. Sandau, and Pierre Ayotte
1014 [ Abstract ] [ Full ] [ PDF ]