Fellowships, Grants, and Awards
For more information on job openings in the environmental health sciences, see EHP's Career Opportunities page. For more information on employment and training at the NIEHS, see http://www.niehs.nih.gov/external/emptrain.htm. Complete information on NIH funding opportunities and notices is available at http://grants.nih.gov/grants/guide/index.html.
For advertisers only: If you would like to publish a Fellowship, Grant, or Award announcement in EHP, please e-mail Erin Dooley at dooley@niehs.nih.gov.
Early Detection Research Network: Biomarker Developmental Laboratories (U01)
This funding opportunity announcement (FOA) solicits cooperative agreement applications for Biomarker Developmental Laboratories (BDLs), one of the four components of the Early Detection Research Network (EDRN). EDRN is a national consortium funded to discover, develop, and validate biomarkers for early cancer detection, risk assessment, and the molecular diagnosis and prognosis of early cancer. The BDLs have responsibility for the development and characterization of new, or the refinement of existing, biomarkers and biomarker assays. The other three main components of the EDRN are: the Biomarker Reference Laboratories (BRLs), which serve as Network resources for clinical and laboratory validation of biomarkers; the Clinical Validation Centers (CVCs), which conduct clinical research on the validation of biomarkers in early cancer detection and risk assessment and serve as resource centers for the EDRN by participating in collaborative biomarker validation studies and collaborating with EDRN BDLs and BRLs; and the Data Management and Coordinating Center (DMCC), which supports statistical and computational analyses, informatics infrastructure, and the coordination of network-wide meetings and conferences. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-09-017.html
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral MD/PhD and Other Dual Doctoral Degree Fellows (F30)
The purpose of the Ruth L. Kirschstein National Research Service Awards (Kirschstein-NRSA) is to provide support to individuals for combined MD/PhD and other dual doctoral degree training (e.g. DO/PhD, DDS/PhD, AuD/PhD). The participating Institutes award this Kirschstein-NRSA individual fellowship (F30) to qualified applicants with the potential to become productive, independent, highly trained physician-scientists and other clinician-scientists, including patient-oriented researchers in their scientific mission areas. This funding opportunity supports individual predoctoral F30 fellowships with the expectation that these training opportunities will increase the number of future investigators with both clinical knowledge and skills in basic, translational or clinical research. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-09-207.html
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows (F31)
The purpose of this individual predoctoral research training fellowship is to provide support for promising doctoral candidates who will be performing dissertation research and training in scientific health-related fields relevant to the missions of the participating NIH Institutes and Centers (ICs) during the tenure of the award. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-09-208.html
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellowships (F31) to Promote Diversity in Health-Related Research
The purpose of this individual predoctoral research training fellowship is to improve the diversity of the health-related research workforce by supporting the training of predoctoral students from groups that have been shown to be underrepresented. Such candidates include individuals from underrepresented racial and ethnic groups, individuals with disabilities, and individuals from disadvantaged backgrounds. Detailed eligibility criteria are described in the full announcement. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-09-209.html
Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (F32)
The purpose of this individual postdoctoral research training fellowship is to provide support to promising Fellowship Applicants with the potential to become productive, independent investigators in scientific health-related research fields relevant to the missions of participating NIH Institutes and Centers. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-09-210.html
Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Senior Fellows (F33)
The National Institutes of Health (NIH) awards individual senior level research training fellowships to experienced scientists who wish to make major changes in the direction of their research careers or who wish to broaden their scientific background by acquiring new research capabilities as independent investigators in research fields relevant to the missions of participating NIH Institutes and Centers. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-09-211.html
Exploring Linkages Between Health Outcomes and Environmental Hazards,
Exposures, and Interventions for Public Health Tracking and Risk Management
The EPA, as part of its Science to Achieve Results (STAR) program, is seeking applications to develop new or improved environmental public health indicators (EPHIs) to build linkages between environmental hazards, human exposures, and public health outcomes. The aim of the research is to develop indicators that can be used for long-term tracking and surveillance of environmental public health, making better informed decisions, and assessing the actual impacts of environmental risk management decisions. Proposed projects should capitalize on existing knowledge bases, data sources, or cohorts to develop EPHIs that reflect a better understanding of the relationships between environmental conditions, human exposure, and/or public health outcomes. Novel application of statistical methods or models may be needed to establish probable relationships between existing datasets or investigate the consequences of environmental actions and policy changes. The complete version of this announcement is available at http://epa.gov/ncer/rfa/2009/2009_star_ephi.html
Advancing Public Health Protection through Water Infrastructure Sustainability
The U.S. EPA, as part of its Science to Achieve Results (STAR) program, is seeking new and innovative research applications that link opportunities to advance public health protection with improvements in the condition and function of the water infrastructure. For purposes of this RFA, the water infrastructure includes centralized and decentralized systems that convey, store, and distribute potable and non-potable water and collect and manage municipal and industrial wastewater, stormwater, and on-site rainwater. Innovation can take the form of wholly new applications or applications that build on existing knowledge and
approaches for new uses. The focus of the solicitation is on improving the effectiveness of the water infrastructure for protecting public health. Projects should clearly demonstrate an integrated, multi-disciplinary approach that leads to advances in design, operation, and management of the water infrastructure and should directly tie those advances to public health protection in conjunction with improving water efficiency and reducing energy
requirements. The complete version of this announcement is available at http://epa.gov/ncer/rfa/2009/2009_star_water_infrastructure.html
Recovery Act Limited Competition: Biomedical Research, Development, and Growth to Spur the Acceleration of New Technologies (BRDG-SPAN) Pilot Program (RC3)
This Funding Opportunity Announcement (FOA), supported by funds provided to the NIH under the American Recovery & Reinvestment Act of 2009 ("Recovery Act" or "ARRA"), Public Law 111-5, solicits grant applications for a new initiative called Biomedical Research, Development, and Growth to Spur the Acceleration of New Technologies (BRDG-SPAN) Pilot Program (RC3). The purpose of this pilot program is to address the funding gap between promising research and development (R&D) and transitioning to the market -- often called the "Valley of Death -- by contributing to the critical funding needed by applicants to pursue the next appropriate milestone(s) toward ultimate commercialization; i.e., to carry out later stage research activities necessary to that end. This program aims to accelerate the transition of research innovations and technologies toward the development of products or services that will improve human health, help advance the mission of NIH and its Institutes and Centers (ICs), and create significant value and economic stimulus. This program also aims to foster partnerships among a variety of research and development (R&D) collaborators working toward these aims. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-09-008.html
Recovery Act Limited Competition: Small Business Catalyst Awards for Accelerating Innovative Research (R43)
This NIH Funding Opportunity Announcement (FOA), supported by funds provided to the NIH under the American Recovery & Reinvestment Act of 2009 ("Recovery Act" or "ARRA"), Public Law 111-5, invites grant applications from small business concerns that propose to accelerate innovation through high risk, high reward research and development (R&D) that has commercial potential and is relevant to the mission of the NIH. The Small Business Catalyst Award is further expected to support entrepreneurs of exceptional creativity, drawn from scientific and technological environments beyond NIH, who propose pioneering and possibly transformative approaches to addressing major biomedical or behavioral challenges with the potential for downstream commercial development. The Small Business Catalyst Award for Accelerating Innovative Research funding opportunity seeks to encourage fresh research perspectives and approaches to serve the mission of NIH. In particular, applications from small business concerns without a history of NIH Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) support may receive funding priority. Solicited are applications for support for projects that have the potential to generate high impact results (e.g., products, processes or services) and/or innovative research applications, research tools, techniques, devices, inventions, or methodologies. The outcomes of the research supported should have potential to lead to products that will improve public health and create significant value and economic stimulus. This FOA solicits early-stage ideas that promise to lead to major leaps forward in capabilities important to serving the mission of NIH rather than incremental improvements of existing technologies. In accord with the funding priority of this initiative to attract applicants without a history of SBIR/STTR support from NIH, the focus of the projects solicited by this FOA is on early stage technology development. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-09-009.html
Joint US – UK Research Program: Environmental Behavior, Bioavailability and Effects of Manufactured Nanomaterials
The US EPA, as part of its Science to Achieve Results (STAR) program, in conjunction with the UK Environmental Nanoscience Initiative [a collaborative initiative funded by the UK Natural Environment Research Council (NERC); the UK Engineering and Physical Sciences Research Council (EPSRC); the UK Government
Department of Environment, Food and Rural Affairs (DEFRA); and the Environment Agency of England and Wales)], is seeking joint applications from US and UK partners that: (1) propose integrated model(s) of fate, behavior, bioavailability and effects for several important and representative nanomaterial classes over key environmental pathways using intrinsic material properties and life cycle analysis as a starting point for model development;
(2) validate and refine these model(s) through interdisciplinary research, addressing key assumptions and areas of uncertainty; and (3) develop effective methods and tools to detect, assess, and monitor the presence of nanomaterials in biological and environmental samples. The outputs of this program will be used to further scientific understanding of the fate, behavior, bioavailability and effects of nanomaterials and risk management policy development. The complete version of this announcement is available at http://epa.gov/ncer/rfa/2009/2009_uk_nano.html
Recovery Act Limited Competition: Academic Research Enhancement Award (R15)
This NIH Funding Opportunity Announcement is supported by funds provided to the NIH under the American Recovery & Reinvestment Act of 2009 ("Recovery Act" or "ARRA"), Public Law 111-5. The purpose of the Academic Research Enhancement Award (AREA) program is to stimulate research in educational institutions that provide baccalaureate or advanced degrees for a significant number of the Nation's research scientists, but that have not been major recipients of NIH support. These AREA grants create opportunities for scientists and institutions otherwise unlikely to participate extensively in NIH programs, to contribute to the Nation's biomedical and behavioral research effort. AREA grants are intended to support small-scale health-related research projects proposed by faculty members of eligible, domestic institutions. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-09-007.html
NIH Small Research Grant Program (Parent R03)
The NIH Investigator-Initiated Small Grant (R03) funding opportunity supports small research projects that can be carried out in a short period of time with limited resources. Investigator-initiated research, also known as unsolicited research, is research funded as a result of an investigator submitting a research grant application to NIH in an investigator's area of interest and competency. The R03 grant mechanism supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. All investigator-initiated small grant applications described in this announcement will be assigned to NIH Institutes and Centers (ICs) according to standard Public Health Service (PHS) referral guidelines and specific program interests. Investigators are strongly encouraged to consult the list of participating ICs and special research interests. See http://grants.nih.gov/grants/guide/contacts/pa-09-163_contacts.htm and the R03 Web site at http://grants.nih.gov/grants/funding/r03.htm. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-09-163.html
NIH Exploratory/Developmental Research Grant Program (Parent R21)
The Exploratory/Developmental Grant (R21) mechanism is intended to encourage exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. All investigator-initiated exploratory/developmental grant applications described in this announcement will be assigned to NIH Institutes and Centers (ICs) according to standard Public Health Service (PHS) referral guidelines and specific program interests. Investigators are strongly encouraged to consult the list of participating ICs and special research interests. See http://grants.nih.gov/grants/guide/contacts/pa-09-164_contacts.htm and the R21 Web site at http://grants.nih.gov/grants/funding/r21.htm. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-09-164.html
Short Term Career Development Award in the Environmental Health Sciences for Established Investigators (K18)
The purpose of these short term career development awards is to allow established, well funded clinician investigators to expand research programs to answer questions relevant to the environmental health sciences, and to provide established environmental health sciences research investigators the tools to expand their efforts to translational research. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-09-090.html
Application and Use of Transformative Emerging Technologies in Cancer Research (R21)
This Funding Opportunity Announcement (FOA) issued by the National Cancer Institute, National Institutes of Health, solicits grant applications proposing exceptionally innovative, high risk, original and/or unconventional research projects focused on evaluating the performance of emerging, potentially transformative molecular and cellular analysis technologies within the context of an appropriate cancer-relevant biological system. The emphasis of this FOA is on the application of emerging molecular and cellular analysis tools with the potential to (i) create new or challenge existing scientific and technological paradigms and/or (ii) overcome technological barriers in important areas of cancer research. Projects must clearly demonstrate potential to produce a major impact in a broad area of biomedical or cancer-relevant research through application to a relevant biological system. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program. Several IMAT FOAs of identical or closely related scientific scope using various funding mechanisms are available. To facilitate selection, a separate Notice in the NIH Guide for Grants and Contracts provides brief cross-comparison and links to all the IMAT FOAs. See NOT-CA-09-007. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-09-006.html
Application and Use of Transformative Emerging Technologies in Cancer Research (R33)
This Funding Opportunity Announcement (FOA) issued by the National Cancer Institute, National Institutes of Health, solicits grant applications proposing exceptionally innovative, high risk, original and/or unconventional research projects focused on evaluating the performance of emerging, potentially transformative molecular and cellular analysis technologies within the context of an appropriate cancer-relevant biological system. The emphasis of this FOA is on the application of emerging molecular and cellular analysis tools with the potential to (i) create new or challenge existing scientific and technological paradigms and/or (ii) overcome technological barriers in important areas of cancer research. Projects must clearly demonstrate potential to produce a major impact in a broad area of biomedical or cancer-relevant research through application to a relevant biological system. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program. Several IMAT FOAs of identical or closely related scientific scope using various funding mechanisms are available. To facilitate selection, a separate Notice in the NIH Guide for Grants and Contracts provides brief cross-comparison and links to all the IMAT FOAs. See NOT-CA-09-007. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-09-007.html
Innovative Technology Development for Cancer Research (R21)
This Funding Opportunity Announcement (FOA) issued by the National Cancer Institute, National Institutes of Health, solicits grant applications proposing exceptionally innovative, high risk, original and/or unconventional exploratory research projects focused on the inception and early stage development of highly innovative cancer-relevant technologies. The emphasis of this FOA is on the development of technically innovative molecular and cellular analysis tools with the potential to (i) create new or challenge existing scientific and technological paradigms and/or (ii) overcome technological barriers in important areas of cancer research. Projects must clearly demonstrate potential to produce a major impact in a broad area of biomedical or cancer-relevant research. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program. Several IMAT FOAs of identical or closely related scientific scope using various funding mechanisms are available. To facilitate selection, a separate Notice in the NIH Guide for Grants and Contracts provides brief cross-comparison and links to all the IMAT FOAs. See NOT-CA-09-007. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-09-008.html
Innovative Toxicity Assays of Pollutants, Therapeutics, and Drugs (SBIR [R43/R44])
This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research grant applications from small business concerns that propose to develop, standardize, and validate new and innovative assays, integrated strategies, or batteries of assays that determine or predict specific organ toxicities (e.g., ocular, dermal, hematotoxicity, cardiotoxicity, gastrointestinal toxicity, hepatotoxicity, nephrotoxicity, ototoxicity, olfactory loss, bladder toxicity, neurotoxicity, pulmonary toxicity, endocrine toxicity, and pancreatic beta cell toxicity), resulting from both acute and chronic exposures to various chemicals, environmental pollutants, biologics and therapeutic molecules or drugs. In addition, this FOA encourages the development, standardization, and validation of new models of arthritis, convulsion, infection and shock. New approaches for high throughput toxicity screening that involve the use of molecular endpoints, computer modeling, proteomics, genomics and epigenomics and the development of virtual tissues are also encouraged as are development of 3-dimensional organ models for toxicity evaluation. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-09-006.html
Innovative Toxicity Assays of Pollutants, Therapeutics, and Drugs (STTR [R41/R42])
This Funding Opportunity Announcement (FOA) encourages Small Business Technology Transfer grant applications from small business concerns that propose to develop, standardize, and validate new and innovative assays, integrated strategies, or batteries of assays that determine or predict specific organ toxicities (e.g., ocular, dermal, hematotoxicity, cardiotoxicity, gastrointestinal toxicity, hepatotoxicity, nephrotoxicity, ototoxicity, olfactory loss, bladder toxicity, neurotoxicity, pulmonary toxicity, endocrine toxicity, and pancreatic beta cell toxicity), resulting from both acute and chronic exposures to various chemicals, environmental pollutants, biologics and therapeutic molecules or drugs. In addition, this FOA encourages the development, standardization, and validation of new models of arthritis, convulsion, infection and shock. New approaches for high throughput toxicity screening that involve the use of molecular endpoints, computer modeling, proteomics, genomics and epigenomics and the development of virtual tissues are also encouraged as are development of 3-dimensional organ models for toxicity evaluation. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-09-007.html
Research to Advance Vaccine Safety (R01)
This Funding Opportunity Announcement, entitled Research to Advance Vaccine Safety, is issued by the National Institutes of Health and encourages Research Project Grant (R01) applications from institutions/organizations that propose to support research that will contribute to the overall understanding of vaccine safety. This R01 research opportunity invites studies that address scientific areas potentially relevant to vaccine safety such as 1) physiological and immunological responses to vaccines and vaccine components, 2) how genetic variations affect immune/physiological responses that may impact vaccine safety, 3) identification of risk factors and biological markers that may be used to assess whether there is a relationship between certain diseases or disorders and licensed vaccines, or 4) the application of genomic/molecular technologies to improve knowledge of vaccine safety. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-256.html
Research to Advance Vaccine Safety (R21)
This Funding Opportunity Announcement (FOA), entitled Research to Advance Vaccine Safety, is issued by the National Institutes of Health and encourages Exploratory/Developmental (R21) grant applications from institutions/organizations that propose to support research that will contribute to the overall understanding of vaccine safety. This R21 research opportunity invites studies that address scientific areas potentially relevant to vaccine safety such as 1) physiological and immunological responses to vaccines and vaccine components, 2) how genetic variations affect immune/physiological responses that may impact vaccine safety, 3) identification of risk factors and biological markers that may be used to assess whether there is a relationship between certain diseases or disorders and licensed vaccines, or 4) the application of genomic/molecular technologies to improve knowledge of vaccine safety. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-257.html
Chronic Fatigue Syndrome: Pathophysiology and Treatment (R01)
This Funding Opportunity Announcement issued by the Office of Research on Women's Health and co-sponsoring Institutes and Centers of the National Institutes of Health (NIH) encourages investigator(s)-initiated applications that propose to examine the etiology, diagnosis, pathophysiology, and treatment of chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME/CFS) in diverse groups and across the lifespan. Innovative applications that address gaps in the understanding of the environmental and biological risk factors, the determinants of heterogeneity among patient populations, and the common mechanisms influencing the multiple body systems that are affected in CFS are encouraged. The NIH is particularly interested in funding interdisciplinary research that will enhance our knowledge of the disease process and provide evidence based solutions to improve the diagnosis, treatment, and quality of life of all persons with CFS. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-246.html
Chronic Fatigue Syndrome: Pathophysiology and Treatment (R21)
This Funding Opportunity Announcement issued by the Office of Research on Women's Health and co-sponsoring Institutes and Centers of the National Institutes of Health (NIH) encourages investigator(s)-initiated applications that propose to examine the etiology, diagnosis, pathophysiology, and treatment of chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME/CFS) in diverse groups and across the lifespan. Innovative applications that address gaps in the understanding of the environmental and biological risk factors, the determinants of heterogeneity among patient populations, and the common mechanisms influencing the multiple body systems that are affected in CFS are encouraged. The NIH is particularly interested in funding interdisciplinary research that will enhance our knowledge of the disease process and provide evidence based solutions to improve the diagnosis, treatment, and quality of life of all persons with CFS. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-247.html
Metals in Medicine (R01)
The objective of this Funding Opportunity Announcement, issued by the National Institute of General Medical Sciences, National Cancer Institute, National Institute of Environmental Health Sciences, and the Office of Dietary Supplements, National Institutes of Health is to encourage research that bridges the areas of inorganic chemistry and medicine. The mechanisms by which organisms control transition metal ions and the roles of these metals in cellular regulation and signaling in health and disease are of principal interest. The interactions of synthetic inorganic complexes with living systems and their components are an additional area of interest. These areas are linked by the need to involve researchers having a deep understanding of inorganic chemistry in medically relevant research. Much of the work is expected to involve collaborations including chemists, biologists, and medical researchers. The results will be relevant to understanding the mechanisms of metal handling by biological systems and the basic cellular roles underlying the nutritional requirement for essential metals. It is expected that this research will also contribute to the identification of new targets for drug discovery, diagnostics, and future therapeutic approaches involving metal complexes, although drug development, per se, is not a focus of the program. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-251.html
Small Grants Program for Cancer Epidemiology (R03)
This funding opportunity announcement (FOA), issued by the National Cancer Institute, encourages the submission of Small Research Grant (R03) applications for research on cancer etiology and epidemiology. The overarching goal of this FOA is to provide support for pilot projects, testing of new techniques, secondary analyses of existing data, development and validation of measurement methods, linkage of genetic polymorphisms with other variables related to cancer risk, and development of innovative projects for more comprehensive research in cancer etiology and epidemiology. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-237.html
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32)
The National Institutes of Health (NIH) will award Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32) to eligible institutions as the primary means of supporting predoctoral and postdoctoral research training to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the Nation's biomedical, behavioral and clinical research agenda. The primary objective of the T32 program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program supports predoctoral, postdoctoral and short term research training programs at domestic institutions of higher education with the T32 funding mechanism. Note that programs solely for short-term research training should not apply to this announcement, but rather the separate (T35) NRSA Short-Term Institutional program exclusively reserved for short-term programs (see PA-08-227). The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-226.html
Ruth L. Kirschstein National Research Service Award Short-Term Institutional Research Training Grants (T35)
The National Institutes of Health (NIH) will award Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grants (T35) to eligible institutions to develop or enhance research training opportunities for individuals interested in careers in biomedical, behavioral and clinical research. Many of the NIH Institutes and Centers (ICs) use this grant mechanism exclusively to support intensive, short-term research training experiences for students in health professional schools during the summer. In addition, the Short-Term Institutional Research Training Grant may be used to support other types of predoctoral and postdoctoral training in focused, often emerging scientific areas relevant to the mission of the funding IC. The proposed training must be in either basic, behavioral or clinical research aspects of the health-related sciences. This program is intended to encourage graduate and/or health professional students to pursue research careers by exposure to and short-term involvement in the health- related sciences. The training should be of sufficient depth to enable the trainees, upon completion of the program, to have a thorough exposure to the principles underlying the conduct of research. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-227.html
Fogarty International Research Collaboration – Basic Biomedical (FIRCA-BB) Research Award (R03)
This Funding Opportunity Announcement (FOA), the "Fogarty International Research Collaboration – Basic Biomedical (FIRCA-BB) Research Award" program, facilitates collaborative basic biomedical research between scientists supported by the National Institutes of Health (NIH) and investigators in low- to middle-income countries (LMIC). All non-AIDS-related biomedical research topics that are supported by the NIH, including basic, clinical, and applied research that does not involve behavioral or social science topics and techniques, are eligible for inclusion under the FIRCA-BB program. Special consideration will be given to proposed research that addresses significant global health problems, particularly those of high relevance to an LMIC country or region. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-222.html
Fogarty International Research Collaboration
Behavioral and Social Sciences (FIRCA-BSS) Research Award (R03)
This Funding Opportunity Announcement (FOA), the "Fogarty International Research Collaboration – Behavioral and Social Sciences (FIRCA-BSS) Research Award" facilitates collaborative behavioral and social sciences research between scientists supported by the National Institutes of Health (NIH) and investigators in low- and middle-income countries (LMIC). Special consideration will be given to proposed research that addresses significant global health problems, particularly those of high relevance to an LMIC country or region. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-223.html
Using Systems Science Methodologies to Protect and Improve Population Health (R21)
This funding opportunity announcement (FOA) is being issued by the Office of Behavioral and Social Sciences Research (OBSSR) of the National Institutes of Health (NIH) with participation from the following NIH components: FIC, NCI, NIA, NICHD, NCCAM, NHLBI, NIEHS, NIMH, NIAAA, NIDCR, NIDA, ODP, and ODS. This FOA solicits Exploratory/Developmental (R21) applications from institutions/organizations that propose to apply one or more specific system science methodologies (identified in Section I.1 – "Background", of this announcement) to public health and health care systems problems and contribute knowledge that will enhance effective decision making around the development of and prioritization of policies, interventions, and programs to improve population health, especially where resources are limited and only a limited number of programs/policies/interventions can be implemented. Applicants are encouraged to submit projects that tackle "policy resistant" health problems (i.e., ones in which the effects of planned interventions, programs or policies tend to be delayed, diluted or defeated by responses of the system to the intervention itself) using a systems science methodology. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-224.html
Exploratory Collaborations with National Centers for Biomedical Computing (R21)
This funding opportunity announcement is for projects from individual-investigators or small groups to collaborate with the NIH Roadmap for Medical Research National Centers for Biomedical Computing (NCBCs). For a description of the NCBCs see http://www.bisti.nih.gov/ncbc/. The intention of the collaborating projects is to engage researchers across the nation in building an excellent biomedical computing environment, using the computational tools and biological and behavioral application drivers of the funded NCBCs as foundation stones. This FOA is intended to support exploratory biomedical informatics and computational biology research—applications should be innovative, with high risk/high impact in new areas that are lacking preliminary data or development. Applications for R21 awards should describe projects distinct from those supported through the traditional R01 mechanism. For example, long-term projects, or projects designed to increase knowledge in a well-established area will not be considered for R21 awards. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-183.html
Collaborations with National Centers for Biomedical Computing (R01)
This funding opportunity announcement is for projects from individual-investigators or small groups to collaborate with the NIH Roadmap for Medical Research National Centers for Biomedical Computing (NCBCs). For a description of the NCBCs see http://www.bisti.nih.gov/ncbc/. The intention of the collaborating projects is to engage researchers across the nation in building an excellent biomedical computing environment, using the computational tools and biological and behavioral application drivers of the funded NCBCs as foundation stones. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-184.html
Millennium Promise Awards: Non-communicable Chronic Diseases Research Training Program (NCoD) (D43)
This research training program is designed to build research capacity in low- and middle-income countries (LMICs) in the fields related to cancer, cerebrovascular disease including stroke, lung disease including chronic obstructive pulmonary disease (COPD) and environmental factors including indoor air pollution, and obesity and lifestyle factors related to these conditions as well as genetics of non-communicable diseases. The institutions applying can be domestic or foreign, but have to exhibit the ability to do such training, and must exhibit that they have existing research programs in these fields. The complete version of this announcement is available at: http://grants.nih.gov/grants/guide/pa-files/PAR-08-175.html
NIH Support for Conferences and Scientific Meetings (Parent R13/U13)
The purpose of the NIH Research Conference Grant Program (R13 and U13) is to support high quality conferences/scientific meetings that are relevant to the scientific mission of the NIH and to the public health. A conference/scientific meeting is defined as a gathering, symposium, seminar, scientific meeting, workshop or any other organized, formal meeting where persons assemble to coordinate, exchange, and disseminate information or to explore or clarify a defined subject, problem, or area of knowledge. Each NIH Institute and Center (IC) has a scientific purview and different program goals and initiatives that evolve over time. Prior to preparing an application, it is critical that all applicants consult the appropriate IC representative listed in the R13/U13 Website (http://grants.nih.gov/grants/funding/r13/) to obtain current information about IC specific program priorities and policies. This action is of utmost importance because applications with marginal or no relevance to the participating Institutes will not be accepted for review or possible funding. In addition, applicants are encouraged to consult the Frequently Asked Questions Website for more detailed information about this program: http://grants.nih.gov/grants/funding/r13/index.htm The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PA-08-149.html
Midcareer Investigator Award in Patient-Oriented Research (K24)
The purpose of the Midcareer Investigator Award in Patient-Oriented Research is to provide support to mid-career health-professional doctorates or equivalent who are typically at the Associate Professor level or the equivalent (see Section III. Eligible Individuals) for protected time to devote to patient-oriented research (POR) and to act as research mentors primarily for clinical residents, clinical fellows and/or junior clinical faculty. The intent of this award is two-fold: 1) to enable mid-career clinician scientists to devote more time and to augment their capabilities in patient-oriented research; and 2) to enable mid-career clinical scientists to mentor new clinical investigators in the conduct of patient-oriented research. An award recipient who continues to have an independent peer-reviewed patient-oriented research program and continues to provide mentoring to new investigators can continue to contribute to the overall goals of the program after being promoted to Full professor. The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PA-08-151.html
New Technologies for Transient Molecular Complex Characterization (SBIR [R43/R44])
This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to develop new technologies, tools, and/or processes for the study of transient molecular complexes. Depending on the complex, such studies should have the potential for characterizing normal function or disease dysfunction and the effects of potential therapeutic interventions. Awards will be used to create new technologies, tools, and/or processes that will help to study transient molecular complexes that are an integral part of normal cell physiology or that play a role in disease processes. Structural (stoichiometry, localization, symmetry, and overall shape) and kinetic characterization of these short-lived complexes will provide insight leading to a better understanding of normal processes and a means to efficiently search for diagnostics or therapeutic interventions for disease conditions. The complete version of this PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-110.html
New Technologies for Transient Molecular Complex Characterization (STTR [R41/R42])
This Funding Opportunity Announcement (FOA) solicits Small Business Technology Transfer (STTR) grant applications from small business concerns (SBCs) that propose to develop new technologies, tools, and/or processes for the study of transient molecular complexes. Depending on the complex, such studies should have the potential for characterizing normal function or disease dysfunction and the effects of potential therapeutic interventions. Awards will be used to create new technologies, tools, and/or processes that will help to study transient molecular complexes that are an integral part of normal cell physiology or that play a role in disease processes. Structural (stoichiometry, localization, symmetry, and overall shape) and kinetic characterization of these short-lived complexes will provide insight leading to a better understanding of normal processes and a means to efficiently search for diagnostics or therapeutic interventions for disease conditions. The complete version of this PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-111.html
In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk (R01)
This Funding Opportunity Announcement (FOA) issued by the National Cancer Institute (NCI), the National Institute of Environmental Health Sciences (NIEHS), and the Office of Dietary Supplements (ODS), encourages innovative preclinical research applications that will enhance the understanding of the relationship between exposure(s) to bioactive food components and/or environmental chemicals in utero, hormonal and growth-factor response, gene expression or epigenetic changes, and subsequent mammary cancer risk in preclinical models. Although much evidence suggests that dietary components are linked to cancer prevention, the specific nutrients, sites of action, and role of exposure in utero remain elusive. Similarly, there are data suggesting a role for environmental agents such as mycotoxins, heterocyclic amines, and environmental chemicals with endocrine activity in the etiology of mammary cancer but the doses, windows of susceptibility, and mechanisms are unclear. This FOA encourages applications that apply new high-throughput genomic, epigenomic, proteomic, and metabolomic technologies to determine how dietary exposures in utero influence adult breast cancer susceptibility. The resulting information will help define effective maternal dietary intervention strategies for breast cancer prevention in her offspring. The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PA-08-141.html
In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk (R21)
This Funding Opportunity Announcement (FOA) issued by the National Cancer Institute (NCI), the National Institute of Environmental Health Sciences (NIEHS), and the Office of Dietary Supplements (ODS), encourages innovative preclinical research applications that will enhance the understanding of the relationship between exposure(s) to bioactive food components and/or environmental chemicals in utero, hormonal and growth-factor response, gene expression or epigenetic changes, and subsequent mammary cancer risk in preclinical models. Although much evidence suggests that dietary components are linked to cancer prevention, the specific nutrients, sites of action, and role of exposure in utero remain elusive. Similarly, there are data suggesting a role for environmental agents such as mycotoxins, heterocyclic amines, and environmental chemicals with endocrine activity in the etiology of mammary cancer but the doses, windows of susceptibility, and mechanisms are unclear. This FOA encourages applications that apply new high-throughput genomic, epigenomic, proteomic, and metabolomic technologies to determine how dietary exposures in utero influence adult breast cancer susceptibility. The resulting information will help define effective maternal dietary intervention strategies for breast cancer prevention in her offspring. The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PA-08-141.html
Genetic Screens to Enhance Zebrafish Research (R01)
This FOA encourages investigator-initiated applications designed to exploit the power of the zebrafish as a ertebrate model for biomedical and behavioral research. Applications proposing to develop new genetic screens of high priority to the zebrafish community that will advance the detection and characterization of genes, pathways, and phenotypes of interest in development and aging, organ formation, neural processes, behavior, sensory processes, physiological processes, and disease processes are welcome. This effort stems from an NIH initiative developed by the Institutes and Centers of the Trans-NIH Zebrafish Coordinating Committee (TZCC) under the co-chairmanship of NICHD and NIDDK. The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PAR-08-138.html
Enhancing Zebrafish Research with Research Tools and Techniques (R01)
This FOA encourages investigator-initiated applications designed to exploit the power of the zebrafish as a vertebrate model for biomedical and behavioral research. Applications proposing to develop new research tools or techniques that are of high priority to the zebrafish community and that will advance the detection and characterization of genes, pathways, and phenotypes of interest in development and aging, organ formation, neural processes, behavior, sensory processing, physiological processes, and disease processes are welcome. This effort stems from an NIH initiative developed by the Institutes and Centers of the Trans-NIH Zebrafish Coordinating Committee (TZCC) under the co-chairmanship of NICHD and NIDDK. The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PAR-08-139.html
The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R01)
The purposes of this FOA are to: 1) improve the measurement of racial /ethnic discrimination in health care delivery systems through improved instrumentation, data collection, and statistical/analytical techniques; 2) enhance understanding of the influence of racial/ethnic discrimination in health care delivery and its association with disparities in disease incidence, treatment, and outcomes among disadvantaged racial/ethnic minority groups; and 3) reduce the prevalence of racial/ethnic health disparities through the development of interventions to reduce the influence of racial/ethnic discrimination in health care delivery systems in the United States (U.S.).
For the purposes of this FOA, health care delivery is defined as the provision or receipt of a broad range of health-related services including preventive, primary, ambulatory and in-patient, emergency, specialty and long-term care. Health care delivery systems are defined as insurance plans, hospitals, clinics, private physician offices, or public and community health facilities that provide or finance health care delivery. The complete version of the PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-083.html
The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R21)
The goals of this funding opportunity are to: 1) improve the measurement of racial /ethnic discrimination in health care delivery systems through improved instrumentation, data collection, and statistical/analytical techniques; 2) enhance understanding of the influence of racial/ethnic discrimination in health care delivery and its association with disparities in disease incidence, treatment, and outcomes among disadvantaged racial/ethnic minority groups; and 3) reduce the prevalence of racial/ethnic health disparities through the development of interventions to reduce the influence of racial/ethnic discrimination in health care delivery systems in the United States (U.S.).
For the purposes of this FOA, health care delivery is defined as the provision or receipt of a broad range of health-related services including preventive, primary, ambulatory and in-patient, emergency, specialty and long-term care. Health care delivery systems are defined as insurance plans, hospitals, clinics, private physician offices, or public and community health facilities that provide or finance health care delivery. The complete version of the PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-084.html
The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R03)
The goals of this funding opportunity are to: 1) improve the measurement of racial /ethnic discrimination in health care delivery systems through improved instrumentation, data collection, and statistical/analytical techniques; 2) enhance understanding of the influence of racial/ethnic discrimination in health care delivery and its association with disparities in disease incidence, treatment, and outcomes among disadvantaged racial/ethnic minority groups; and 3) reduce the prevalence of racial/ethnic health disparities through the development of interventions to reduce the influence of racial/ethnic discrimination in health care delivery systems in the United States.
For the purposes of this FOA, health care delivery is defined as the provision or receipt of a broad range of health-related services including preventive, primary, ambulatory and in-patient, emergency, specialty and long-term care. Health care delivery systems are defined as insurance plans, hospitals, clinics, private physician offices, or public and community health facilities that provide or finance health care delivery. The complete version of the PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-085.html
Pfizer Scholars Grants in Public Health - Junior Faculty Pursuing Community-Based, Public Health Practice Research
Pfizer Inc is proud to sponsor the Pfizer Scholars Grants in Public Health. These awards are meant to support the career development of junior faculty in public health. This educational grant is nationally competitive, and chosen by an independent Academic Advisory Board of recognized leaders in public health. More information is available at http://www.promisingminds.com/AwardDetails.asp x?AwardID=2081
Community Participation in Research (R01)
The National Institutes of Health (NIH) issues this Funding Opportunity Announcement (FOA) to solicit research project (R01) grant applications that propose intervention research on health promotion, disease prevention, and health disparities that communities and researchers jointly conduct.
Community-based participatory research (CBPR) is defined as scientific inquiry conducted in communities and in partnership with researchers. The process of scientific inquiry is such that community members, persons affected by the health condition, disability or issue under study, or other key stakeholders in the community's health have the opportunity to be full participants in each phase of the work (from conception – design – conduct – analysis –interpretation – conclusions – communication of results). CBPR is characterized by substantial community input in the development of the grant application (http://odoerdb2-1.od.nih.gov/oer/training/esaig/cbprsig_IG.htm).
For the purposes of this FOA, intervention research is quasi-experimental research projects that seek to influence preventive behaviors, treatment adherences, complementary behaviors, and related attitudes and beliefs. Natural experiments also may fall under the interventions rubric. Examples include, and are not limited to promotion of physical activity-friendly neighborhoods; tobacco, alcohol and drug abuse prevention among youth; a community-led action plan for cancer, hypertension and cardiovascular disease prevention and control in minority populations; establishing safer work practices among agricultural workers in rural areas; nutrition and reducing childhood obesity; HIV/AIDS and STD prevalence among young adults; promoting infant mental health; and reducing health disparities. The complete version of this PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-074.html.
Community Participation Research Targeting the Medically Underserved (R01)
The National Institutes of Health (NIH) issues this Funding Opportunity Announcement (FOA) with a special review to solicit research project (R01) grant applications that propose research on health promotion, disease prevention, and health disparities that is jointly conducted by communities and researchers and targets medically underserved areas (MUAs) and medically underserved populations (MUPs) as defined by the Department of Health and Human Services (DHHS) Health Resources and Services Administration (HRSA).
Community-based participatory research (CBPR) is defined as scientific inquiry conducted in communities and in partnership with researchers. The process of scientific inquiry is such that community members, persons affected by the health condition, disability or issue under study, or other key stakeholders in the community's health have the opportunity to be full participants in each phase of the work (from conception – design – conduct – analysis – interpretation – conclusions – communication of results). CBPR is characterized by substantial community input in the development of the grant application (http://odoerdb2-1.od.nih.gov/oer/training/esaig/cbprsig_IG.htm). The complete version of this PAR is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-075.html
Community Participation Research Targeting the Medically Underserved (R21)
The National Institutes of Health (NIH) issues this Funding Opportunity Announcement (FOA) with a special review to solicit exploratory/developmental (R21) grant applications that propose research on health promotion, disease prevention, and health disparities that is jointly conducted by communities and researchers and targets medically underserved areas (MUAs) and medically underserved populations (MUPs) as defined by the Department of Health and Human Services (DHHS) Health Resources and Services Administration (HRSA).
Community-based participatory research (CBPR) is defined as scientific inquiry conducted in communities and in partnership with researchers. The process of scientific inquiry is such that community members, persons affected by the health condition, disability or issue under study, or other key stakeholders in the community's health have the opportunity to be full participants in each phase of the work (from conception – design – conduct – analysis – interpretation – conclusions – communication of results). CBPR is characterized by substantial community input in the development of the grant application (http://odoerdb2-1.od.nih.gov/oer/training/esaig/cbprsig_IG.htm). The complete version of this PAR is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-076.html
The Science and Ecology of Early Development (SEED) [R03]
SCOPE: The common characteristic of the small grant is provision of limited funding for a short period of time. Examples of the types of projects that ICs support with the R03 include the following:
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Pilot or feasibility studies
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Secondary analysis of existing data
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Small, self-contained research projects
This Funding Opportunity Announcement (FOA), jointly issued by the Child Development and Behavior Branch (CDBB) and the Demographic and Behavioral Sciences Branch (DBSB) of the National Institute of Child Health and Human Development (NICHD), Division of Epidemiology, Services and Prevention Research of the National Institute on Drug Abuse (NIDA), and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), invites research grant applications that seek to develop or contribute to a comprehensive program of research focused on the mechanisms through which social, economic, cultural, familial and community-level factors, and their interactions, impact the early cognitive, neurobiological, socio-emotional, and physical development of children. Understanding the influence of these mechanisms and the pathways by which they operate is especially important for understanding the impact of available services and the public policies which govern them on the development of children at whom (or at whose families) these policies are often specifically targeted, notably children living in poverty or near the federal poverty line. Arenas of particular relevance include childcare, early childhood education, welfare reform, tax, social services, and work-family policies, as all of these shape the life experiences of children in poverty. Thus, the goal is to generate solid scientific information that would bear directly on these arenas and thus inform policies and the design of service delivery programs that impact child development, whether or not child development is the explicit focus of those policies and services. This FOA extends the seven-year Science and Ecology of Early Development (SEED) initiative and is the outgrowth of an interagency collaborative effort from 2000 through 2004 among the following agencies: 1) U.S. Department of Health and Human Services [NICHD, National Institute of Mental Health (NIMH), NIDA, Administration for Children and Families (ACF), Office of the Assistant Secretary for Planning and Evaluation (ASPE), and the Centers for Disease Control and Prevention (CDC)], and 2) the Department of Education (National Center for Education Statistics, National Center for Education Research, and the National Center for Special Education Research in the Institute of Education Sciences). These agencies have pursued other avenues of supporting research on this topic. NICHD and NIDA have continued to collaborate on this Funding Opportunity Announcement. Details of that earlier initiative can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06-345.html and http://grants.nih.gov/grants/guide/pa-files/PA-07-149.html. The complete version of this PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-068.html.
Nanoscience and Nanotechnology in Biology and Medicine (R01)
Nanoscience and nanotechnology refer to the understanding and control of matter at the atomic, molecular or macromolecular levels, at the length scale of approximately 1–100 nanometers. The purpose of this funding opportunity is to stimulate nanoscience and nanotechnology research approaches that have the potential to make valuable contributions to biology and medicine. Nanoscience and nanotechnology can bring fundamental changes to the study and understanding of biological processes in health and disease, as well as enable novel diagnostics and interventions for treating disease. Thus, advances based on nanotechnology and nanoscience could result in a new era in healthcare. The complete version of this PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-052.html.
Predictive Multiscale Models of the Physiome in Health and Disease (R01)
The goal of this solicitation is to move the field of biomedical computational modeling forward through the development of more realistic and predictive models of health and disease. NIH recognizes the need for sophisticated, predictive, computational models of development and disease that encompass multiple biological scales. These models may be designed to uncover biological mechanisms or to make predictions about clinical outcome and may draw on a variety of data sources including relevant clinical data. Ultimately the models and the information derived from their use will enable biomedical and behavioral researchers and clinicians to better understand, prevent, diagnose and treat the diseases or aberrations in normal development. Specifically this FOA seeks the development of biomedical models that are 1) multiscale, 2) predictive of health and disease states, and 3) that must include models at higher scales of the physiome. The complete version of this PAR is available at: http://grants.nih.gov/grants/guide/pa-files/PAR-08-023.html
NIAID Science Education Awards (R25)
This funding opportunity announcement (FOA) solicits applications from applicant organizations that propose creative and innovative research education programs that will 1) increase the public's understanding of biomedical research, or 2) encourage K-12 students to enter areas in biomedical science in the mission area(s) of the National Institute of Allergy and Infectious Diseases (NIAID). The NIH Research Education (R25) grant mechanism is a flexible and specialized mechanism designed to foster the development of biomedical, behavioral, and clinical researchers through creative and innovative research education programs. The complete version of this PAR is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-003.html.
