| Toxicogenomics through the Eyes of Informatics: Conference Overview and Recommendations Kenneth Olden,1 Neysa Call,2 Bruno Sobral,2 and
Robin Oakes2 1National Institute of Environmental Health Sciences, National Institutes
of Health, Department of Health and Human Services, Research Triangle Park,
North Carolina, USA; 2Virginia Bioinformatics Institute, Virginia
Polytechnic Institute and State University, Blacksburg, Virginia, USA Abstract Virginia Bioinformatics Institute, in conjunction with National Institutes of Environmental Health Sciences, hosted a conference, "Toxicogenomics through the Eyes of Informatics," in Bethesda, Maryland, USA, on 12-13 May 2003. Researchers around the world met to discuss how the application of bioinformatics tools, methodologies, and technologies will enhance our understanding of how cells and organisms respond to toxins. Conference topics included statistical methods, quantitative molecular data sets, computational algorithms for data analysis, computational modeling and simulation, challenges and opportunities in computational biology, and information technology infrastructure for data and tool management. This meeting report is a summary of conference presentations, survey results, current toxicogenomics concerns, and future directions of the toxicogenomics community. In conclusion this report discusses toxicogenomics as related to environmental agents, cell-chemical reactions, and gene-environment interactions. Key words: bioinformatics, cell-chemical reactions, environmental agents, toxicogenomics, toxins, Virginia Bioinformatics Institute. Environ Health Perspect 112:805-807 (2004) . doi:10.1289/txg.6799 available via http://dx.doi.org/ [Online 1 April 2004] Address correspondence to B. Sobral, Virginia Bioinformatics Institute, Virginia Tech, Bioinformatics Facility 1 (0477) , Blacksburg, VA 24061 USA. Telephone: (540) 231-1259. Fax: (540) 231-2606. E-mail: necall@vt.edu We thank J. Selkirk from the National Institutes of Environmental Health Sciences for his scientific guidance. We also thank C. Phillips from Virginia Bioinformatics Institute for her assistance with conference arrangements and logistics. The authors declare they have no competing financial interests. Received 14 October 2003 ; accepted 31 March 2004. The full version of this article is available for free in HTML or PDF formats. |